{"id":100,"date":"2023-09-18T15:53:45","date_gmt":"2023-09-18T07:53:45","guid":{"rendered":"http:\/\/www.yaozhiyou.com\/?p=100"},"modified":"2023-09-18T15:53:47","modified_gmt":"2023-09-18T07:53:47","slug":"%e5%8a%b3%e6%8b%89%e6%9b%bf%e5%b0%bclorlatinib-lorbrena","status":"publish","type":"post","link":"https:\/\/yaozhiyou.com\/?p=100","title":{"rendered":"\u52b3\u62c9\u66ff\u5c3clorlatinib-Lorbrena"},"content":{"rendered":"\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"400\" height=\"376\" src=\"http:\/\/www.yaozhiyou.com\/wp-content\/uploads\/2023\/09\/t01a1116b149bd51977.jpg\" alt=\"\" class=\"wp-image-102\" srcset=\"https:\/\/yaozhiyou.com\/wp-content\/uploads\/2023\/09\/t01a1116b149bd51977.jpg 400w, https:\/\/yaozhiyou.com\/wp-content\/uploads\/2023\/09\/t01a1116b149bd51977-300x282.jpg 300w\" sizes=\"auto, (max-width: 400px) 100vw, 400px\" \/><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">\u4ec0\u4e48\u662fLorlatinib\u52b3\u62c9\u66ff\u5c3c\uff1f<\/h2>\n\n\n\n<p>Lorlatinib\u52b3\u62c9\u66ff\u5c3c\u662f\u4e00\u79cd\u5904\u65b9\u836f\uff0c\u7528\u4e8e\u6cbb\u7597\u5df2\u7ecf\u6269\u6563\u5230\u8eab\u4f53\u5176\u4ed6\u90e8\u4f4d\u7684\u67d0\u79cd\u7c7b\u578b\u7684\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u3002<\/p>\n\n\n\n<p>Lorbrena\u4ec5\u5728\u60a8\u7684\u764c\u75c7\u5177\u6709\u7279\u5b9a\u9057\u4f20\u6807\u8bb0\uff08\u5f02\u5e38\u201cALK\u201d\u57fa\u56e0\uff09\u65f6\u4f7f\u7528\u3002\u4f60\u9700\u8981\u57fa\u56e0\u68c0\u6d4b\u662f\u5426\u6709ALK\u53d8\u5f02\u3002<\/p>\n\n\n\n<p>Lorlatinib\u52b3\u62c9\u66ff\u5c3c\u662f\u5728\u5176\u4ed6\u764c\u75c7\u6cbb\u7597\u65e0\u6548\u540e\u7ed9\u4e88\u7684\u3002<\/p>\n\n\n\n<p>Lorlatinib\u52b3\u62c9\u66ff\u5c3c\u5728\u201c\u52a0\u901f\u201d\u7684\u57fa\u7840\u4e0a\u83b7\u5f97\u4e86\u7f8e\u56fd\u98df\u54c1\u548c\u836f\u7269\u7ba1\u7406\u5c40\uff08FDA\uff09\u7684\u6279\u51c6\u3002\u5728\u4e34\u5e8a\u7814\u7a76\u4e2d\uff0c\u6709\u4e9b\u4eba\u5bf9\u8be5\u836f\u6709\u53cd\u5e94\uff0c\u4f46\u8fd8\u9700\u8981\u8fdb\u4e00\u6b65\u7684\u7814\u7a76\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u91cd\u8981\u4fe1\u606f<\/h2>\n\n\n\n<p>\u5982\u679c\u60a8\u670d\u7528\u67d0\u4e9b\u79f0\u4e3a\u5f3aCYP3A\u8bf1\u5bfc\u5242\u7684\u5176\u4ed6\u836f\u7269\uff0c\u8bf7\u4e0d\u8981\u670d\u7528Lorbrena\u3002\u5982\u679c\u60a8\u4e0d\u786e\u5b9a\uff0c\u8bf7\u5411\u60a8\u7684\u533b\u62a4\u4eba\u5458\u54a8\u8be2\u8fd9\u4e9b\u836f\u7269\u7684\u6e05\u5355\u3002<\/p>\n\n\n\n<p>\u544a\u8bc9\u60a8\u7684\u533b\u751f\u60a8\u5f53\u524d\u6240\u6709\u7684\u836f\u7269\u4ee5\u53ca\u60a8\u5f00\u59cb\u6216\u505c\u6b62\u4f7f\u7528\u7684\u4efb\u4f55\u836f\u7269\u3002\u8bb8\u591a\u836f\u7269\u53ef\u4ee5\u76f8\u4e92\u4f5c\u7528\uff0c\u6709\u4e9b\u836f\u7269\u4e0d\u5e94\u8be5\u4e00\u8d77\u4f7f\u7528\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u670d\u7528\u6b64\u836f\u524d<\/h2>\n\n\n\n<p>\u4e3a\u4e86\u786e\u4fddLorbrena\u5bf9\u60a8\u5b89\u5168\uff0c\u8bf7\u544a\u8bc9\u60a8\u7684\u533b\u751f\u60a8\u662f\u5426\u6709\u8fc7\uff1a<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u5fc3\u810f\u95ee\u9898\uff0c\u5982\u201cAV\u963b\u6ede\u201d\uff08\u9664\u975e\u4f60\u6709\u5fc3\u810f\u8d77\u640f\u5668\uff09;<\/li>\n\n\n\n<li>\u80ba\u75c5\uff0c\u547c\u5438\u56f0\u96be;<\/li>\n\n\n\n<li>\u809d\u75c5&nbsp;;<\/li>\n\n\n\n<li>\u6291\u90c1&nbsp;;<\/li>\n\n\n\n<li>\u766b\u75eb\u53d1\u4f5c&nbsp;;&nbsp;\u8981\u4e48<\/li>\n\n\n\n<li>\u9ad8\u80c6\u56fa\u9187\u6216\u7518\u6cb9\u4e09\u916f\uff08\u8840\u6db2\u4e2d\u7684\u4e00\u79cd\u8102\u80aa\uff09\u3002<\/li>\n<\/ul>\n\n\n\n<p><strong>\u5982\u679c\u6bcd\u4eb2\u6216\u7236\u4eb2\u4f7f\u7528Lorlatinib\u52b3\u62c9\u66ff\u5c3c<\/strong><\/p>\n\n\n\n<p>Lorlatinib\u52b3\u62c9\u66ff\u5c3c\u4f1a\u4f24\u5bb3\u672a\u51fa\u751f\u7684\u5a74\u513f\u6216\u5bfc\u81f4\u51fa\u751f\u7f3a\u9677<strong>\u3002<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u5982\u679c\u60a8\u662f\u5973\u6027\uff0c<\/strong>\u5982\u679c\u60a8\u6000\u5b55<strong>\uff0c<\/strong>\u8bf7\u4e0d\u8981\u4f7f\u7528Lorlatinib\u52b3\u62c9\u66ff\u5c3c\u3002\u5728\u5f00\u59cb\u8fd9\u79cd\u6cbb\u7597\u4e4b\u524d\uff0c\u60a8\u53ef\u80fd\u9700\u8981\u8fdb\u884c\u9634\u6027\u598a\u5a20\u8bd5\u9a8c\u3002\u4f7f\u7528\u6709\u6548\u7684\u907f\u5b55\u63aa\u65bd\uff0c\u4ee5\u9632\u6b62\u5728\u60a8\u4f7f\u7528\u8be5\u836f\u7269\u65f6\u6000\u5b55\uff0c\u5e76\u5728\u60a8\u6700\u540e\u4e00\u6b21\u670d\u836f\u540e\u81f3\u5c116\u4e2a\u6708\u3002<\/li>\n\n\n\n<li><strong>\u5982\u679c\u60a8\u662f\u7537\u6027\uff0c<\/strong>\u5982\u679c\u60a8\u7684\u6027\u4f34\u4fa3\u80fd\u591f\u6000\u5b55<strong>\uff0c<\/strong>\u8bf7\u4f7f\u7528\u6709\u6548\u7684\u907f\u5b55\u63aa\u65bd\u3002\u5728\u6700\u540e\u4e00\u6b21\u670d\u836f\u540e\u81f3\u5c11\u4fdd\u63013\u4e2a\u6708\u7684\u751f\u80b2\u63a7\u5236\u3002<\/li>\n\n\n\n<li>\u5982\u679c\u6bcd\u4eb2\u6216\u7236\u4eb2\u4f7f\u7528Lorlatinib\u52b3\u62c9\u66ff\u5c3c\u6000\u5b55\uff0c\u8bf7\u7acb\u5373\u544a\u8bc9\u60a8\u7684\u533b\u751f\u3002<\/li>\n<\/ul>\n\n\n\n<p>Lorlatinib\u52b3\u62c9\u66ff\u5c3c\u53ef\u4ee5\u964d\u4f4e\u6fc0\u7d20\u907f\u5b55\u6548\u679c\uff08\u907f\u5b55\u836f\uff0c\u6ce8\u5c04\u5242\uff0c\u690d\u5165\u7269\uff0c\u76ae\u80a4\u8d34\u7247\uff0c\u9634\u9053\u73af\uff09\u3002\u5411\u60a8\u7684\u533b\u751f\u8be2\u95ee\u5728\u4f7f\u7528\u8be5\u836f\u6cbb\u7597\u671f\u95f4\u4f7f\u7528\u7684\u6700\u4f73\u907f\u5b55\u65b9\u5f0f\u3002<\/p>\n\n\n\n<p><strong>\u4f7f\u7528Lorlatinib\u52b3\u62c9\u66ff\u5c3c\u65f6\u4e0d\u8981\u6bcd\u4e73\u5582\u517b\uff0c<\/strong>\u6700\u540e\u4e00\u6b21\u7ed9\u836f\u540e\u81f3\u5c117\u5929\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"directions\">\u6211\u8be5\u5982\u4f55\u670d\u7528Lorlatinib\u52b3\u62c9\u66ff\u5c3c\uff1f<\/h2>\n\n\n\n<p>\u5b8c\u5168\u6309\u7167\u533b\u751f\u7684\u89c4\u5b9a\u670d\u7528Lorlatinib\u52b3\u62c9\u66ff\u5c3c\u3002\u6309\u7167\u5904\u65b9\u6807\u7b7e\u4e0a\u7684\u6240\u6709\u8bf4\u660e\u8fdb\u884c\u64cd\u4f5c\uff0c\u5e76\u9605\u8bfb\u6240\u6709\u836f\u7269\u6307\u5357\u6216\u8bf4\u660e\u4e66\u3002<\/p>\n\n\n\n<p>\u541e\u4e0b\u6574\u4e2a\u836f\u7247\uff0c\u4e0d\u8981\u538b\u788e\uff0c\u5480\u56bc\u6216\u7834\u788e\u3002<\/p>\n\n\n\n<p>\u6bcf\u5929\u5728\u540c\u4e00\u65f6\u95f4\u670d\u836f\uff0c\u6709\u6216\u6ca1\u6709\u98df\u7269\u3002<\/p>\n\n\n\n<p>\u4e0d\u8981\u4f7f\u7528\u7834\u788e\u6216\u7834\u88c2\u7684\u5e73\u677f\u7535\u8111\u3002<\/p>\n\n\n\n<p>\u5982\u679c\u60a8\u5728\u670d\u7528Lorlatinib\u52b3\u62c9\u66ff\u5c3c\u540e\u4e0d\u4e45\u5455\u5410\uff0c\u8bf7\u4e0d\u8981\u670d\u7528\u53e6\u4e00\u5242\u3002\u7b49\u5230\u4e0b\u4e00\u6b21\u9884\u5b9a\u7684\u5242\u91cf\u65f6\u95f4\u518d\u6b21\u670d\u836f\u3002<\/p>\n\n\n\n<p>\u5728\u5ba4\u6e29\u4e0b\u50a8\u5b58\uff0c\u8fdc\u79bb\u6f6e\u6e7f\u548c\u9ad8\u6e29\u3002<\/p>\n\n\n\n<p>\u672a\u7ecf\u533b\u751f\u5efa\u8bae\uff0c\u4e0d\u8981\u6539\u53d8\u5242\u91cf\u6216\u505c\u6b62\u670d\u7528Lorlatinib\u52b3\u62c9\u66ff\u5c3c\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u63a8\u8350\u7528\u91cf<\/h3>\n\n\n\n<p>Lorlatinib\u52b3\u62c9\u66ff\u5c3c\u7684\u63a8\u8350\u5242\u91cf\u662f\u6bcf\u5929\u53e3\u670d100\u6beb\u514b\uff0c\u996d\u524d\u996d\u540e\u7686\u53ef\u670d\u7528\uff0c\u76f4\u81f3\u75be\u75c5\u8fdb\u5c55\u6216\u4e0d\u53ef\u63a5\u53d7\u7684\u6bd2\u6027\u3002<\/p>\n\n\n\n<p>\u6574\u7247\u541e\u670d\u3002\u4e0d\u8981\u5480\u56bc\uff0c\u538b\u788e\u6216\u5206\u88c2\u836f\u7247\u3002\u5982\u679c\u7247\u5242\u7834\u88c2\uff0c\u7834\u88c2\u6216\u4e0d\u5b8c\u6574\uff0c\u8bf7\u52ff\u6444\u53d6\u3002<\/p>\n\n\n\n<p>\u6bcf\u5929\u5728\u540c\u4e00\u65f6\u95f4\u670d\u7528Lorlatinib\u52b3\u62c9\u66ff\u5c3c\u3002\u5982\u679c\u9519\u8fc7\u5242\u91cf\uff0c\u5219\u53d6\u4e0b\u9519\u8fc7\u7684\u5242\u91cf\uff0c\u9664\u975e\u4e0b\u4e00\u5242\u91cf\u57284\u5c0f\u65f6\u5185\u5230\u671f\u3002\u4e0d\u8981\u540c\u65f6\u670d\u75282\u5242\u4ee5\u5f25\u8865\u9519\u8fc7\u7684\u5242\u91cf\u3002<\/p>\n\n\n\n<p>\u5982\u679c\u5728Lorlatinib\u52b3\u62c9\u66ff\u5c3c\u540e\u51fa\u73b0\u5455\u5410\u4f46\u662f\u7ee7\u7eed\u4e0b\u4e00\u6b21\u9884\u5b9a\u5242\u91cf\uff0c\u5219\u4e0d\u8981\u670d\u7528\u989d\u5916\u7684\u5242\u91cf\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u4e0d\u826f\u53cd\u5e94\u7684\u5242\u91cf\u8c03\u6574<\/h3>\n\n\n\n<p><strong>\u63a8\u8350\u7684\u5242\u91cf\u51cf\u5c11\u662f\uff1a<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u9996\u6b21\u5242\u91cf\u51cf\u5c11\uff1aLorlatinib\u52b3\u62c9\u66ff\u5c3c 75 mg\u6bcf\u65e5\u53e3\u670d\u4e00\u6b21<\/li>\n\n\n\n<li>\u7b2c\u4e8c\u6b21\u5242\u91cf\u51cf\u5c11\uff1aLorlatinib\u52b3\u62c9\u66ff\u5c3c\u6bcf\u5929\u53e3\u670d50\u6beb\u514b<\/li>\n<\/ul>\n\n\n\n<p>\u5bf9\u4e8e\u6bcf\u5929\u53e3\u670d\u4e0d\u80fd\u8010\u53d750\u6beb\u514b\u7684\u60a3\u8005\uff0c\u6c38\u4e45\u6027\u505c\u7528Lorlatinib\u52b3\u62c9\u66ff\u5c3c\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"dosage\"><strong>\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u7684\u5e38\u7528\u6210\u4eba\u5242\u91cf\uff1a<\/strong><\/h2>\n\n\n\n<p>\u6bcf\u5929\u53e3\u670d100\u6beb\u514b\uff0c\u76f4\u5230\u75be\u75c5\u8fdb\u5c55\u6216\u4e0d\u53ef\u63a5\u53d7\u7684\u6bd2\u6027<\/p>\n\n\n\n<p>\u8bc4\u8bba\uff1a \u2013<br>\u5982\u679c\u9519\u8fc7\u5242\u91cf\uff0c\u9664\u975e\u4e0b\u4e00\u6b21\u5242\u91cf\u57284\u5c0f\u65f6\u5185\u5230\u671f\uff0c\u5426\u5219\u670d\u7528\u9519\u8fc7\u7684\u5242\u91cf;&nbsp;\u4e0d\u8981\u540c\u65f6\u670d\u75282\u5242\u4ee5\u5f25\u8865\u9519\u8fc7\u7684\u5242\u91cf\u3002<br>\u2013 \u5982\u679c\u53d1\u751f\u5455\u5410\uff0c\u4e0d\u8981\u518d\u670d\u7528\u4e00\u5242\uff0c\u4f46\u7ee7\u7eed\u670d\u7528\u4e0b\u4e00\u6b21\u9884\u5b9a\u5242\u91cf\u3002<\/p>\n\n\n\n<p>\u7528\u9014\uff1a\u7528\u4e8e\u6cbb\u7597\u60a3\u6709\u95f4\u53d8\u6027\u6dcb\u5df4\u7624\u6fc0\u9176\uff08ALK\uff09\u9633\u6027\u8f6c\u79fb\u6027\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08\u6cbb\u7597\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff09\uff0c\u5176\u75be\u75c5\u8fdb\u5c55\u4e0a\u514b\u91cc\u5511\u66ff\u5c3c\u548c\u8f6c\u79fb\u6027\u75be\u75c5\u6216\u81f3\u5c11\u4e00\u79cd\u5176\u5b83ALK\u6291\u5236\u5242alectinib<a href=\"http:\/\/www.yindushop.com\/tag\/alynni\">\u963f\u6765\u66ff\u5c3c<\/a>\u7b2c\u4e00ALK\u6291\u5236\u5242\u7597\u6cd5\u7528\u4e8e\u8f6c\u79fb\u6027\u75be\u75c5\u6216ceritinib\u8272\u745e\u66ff\u5c3c\u4f5c\u4e3a\u8f6c\u79fb\u6027\u75be\u75c5\u7684\u7b2c\u4e00\u4e2aALK\u6291\u5236\u5242\u7597\u6cd5\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">\u5982\u679c\u6211\u9519\u8fc7\u5242\u91cf\u4f1a\u600e\u4e48\u6837\uff1f<\/h4>\n\n\n\n<p>\u5c3d\u5feb\u670d\u7528\u836f\u7269\uff0c\u4f46\u5982\u679c\u4e0b\u6b21\u5242\u91cf\u5728\u4e0d\u52304\u5c0f\u65f6\u5185\u5230\u671f\uff0c\u5219\u8df3\u8fc7\u9519\u8fc7\u7684\u5242\u91cf\u3002\u4e0d\u8981\u540c\u65f6\u4f7f\u7528\u4e24\u5242\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"overdose\">\u5982\u679c\u6211\u670d\u7528\u8fc7\u91cf\u4f1a\u600e\u4e48\u6837\uff1f<\/h2>\n\n\n\n<p>\u5bfb\u6c42\u7d27\u6025\u533b\u7597\u62a4\u7406120.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"avoid\">\u670d\u7528Lorlatinib\u52b3\u62c9\u66ff\u5c3c\u65f6\u5e94\u8be5\u907f\u514d\u4ec0\u4e48\uff1f<\/h2>\n\n\n\n<p>\u907f\u514d\u670d\u7528\u542b\u6709\u8d2f\u53f6\u91d1\u4e1d\u6843\uff08\u4e2d\u836f\u540d\uff09\u7684\u8349\u836f\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"avoid\">Lorlatinib\u52b3\u62c9\u66ff\u5c3c\u7684\u526f\u4f5c\u7528<\/h2>\n\n\n\n<p>\u5982\u679c\u60a8\u6709\u5bf9Lorlatinib\u52b3\u62c9\u66ff\u5c3c\u8fc7\u654f\u53cd\u5e94\u7684\u8ff9\u8c61\uff0c\u8bf7&nbsp;\u83b7\u5f97\u7d27\u6025\u533b\u7597\u5e2e\u52a9<strong>\uff1a<\/strong>\u8368\u9ebb\u75b9&nbsp;;&nbsp;\u547c\u5438\u56f0\u96be;&nbsp;\u8138\u90e8\uff0c\u5634\u5507\uff0c\u820c\u5934\u6216\u5589\u5499\u80bf\u80c0\u3002<\/p>\n\n\n\n<p>\u5982\u679c\u60a8\u6709\u4ee5\u4e0b\u60c5\u51b5\uff0c\u8bf7\u7acb\u5373\u81f4\u7535\u60a8\u7684\u533b\u751f<\/p>\n\n\n\n<ul 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id=\"interactions\">\u8fd8\u6709\u54ea\u4e9b\u836f\u7269\u4f1a\u5f71\u54cdLorlatinib\u52b3\u62c9\u66ff\u5c3c\uff1f<\/h2>\n\n\n\n<p>\u6709\u65f6\u540c\u65f6\u4f7f\u7528\u67d0\u4e9b\u836f\u7269\u662f\u4e0d\u5b89\u5168\u7684\u3002\u67d0\u4e9b\u836f\u7269\u4f1a\u5f71\u54cd\u60a8\u670d\u7528\u7684\u5176\u4ed6\u836f\u7269\u7684\u8840\u6db2\u6d53\u5ea6\uff0c\u8fd9\u53ef\u80fd\u4f1a\u589e\u52a0\u526f\u4f5c\u7528\u6216\u4f7f\u836f\u7269\u6548\u679c\u964d\u4f4e\u3002<\/p>\n\n\n\n<p>\u8bb8\u591a\u836f\u7269\u53ef\u4ee5\u4e0eLorlatinib\u52b3\u62c9\u66ff\u5c3c\u76f8\u4e92\u4f5c\u7528\u3002\u8fd9\u5305\u62ec\u5904\u65b9\u836f\u548c\u975e\u5904\u65b9\u836f\uff0c\u7ef4\u751f\u7d20\u548c\u8349\u836f\u4ea7\u54c1\u3002\u6b64\u5904\u672a\u5217\u51fa\u6240\u6709\u53ef\u80fd\u7684\u4e92\u52a8\u3002\u544a\u8bc9\u60a8\u7684\u533b\u751f\u60a8\u5f53\u524d\u6240\u6709\u7684\u836f\u7269\u4ee5\u53ca\u60a8\u5f00\u59cb\u6216\u505c\u6b62\u4f7f\u7528\u7684\u4efb\u4f55\u836f\u7269\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u4ec0\u4e48\u662fLorlatinib\u52b3\u62c9\u66ff\u5c3c\uff1f 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